Sotalol - CVCA Cardiac Care for Pets

Sotalol Drug Handout

What is Sotalol?

Sotalol is an oral medication belonging to a group of medications known as antiarrhythmics. Its purpose is to slow the electrical impulses through the heart by blocking how potassium is able to leave the heart cell. It also has a beta blocker effect, decreasing the heart’s response to stress, lowering the heart rate, as well as the risk for certain arrhythmias.

Adverse Effects

Please contact CVCA should any of these symptoms be noted

Negative effect on heart muscle strength resulting in signs of heart failure

Abnormally slow heart rate resulting in lethargy or weakness

Uncommonly causes decreased appetite, vomiting or diarrhea

Rare complication to worsen arrhythmias

Client Information

Can be given with food, but more effective on an empty stomach

Comes in tablet form, but can be reformulated into capsules or flavored liquids

Please do not abruptly stop the medication, skip or change dosages without veterinary approval

Often used in combination with other antiarrhythmic medications (Mexiletine, Digoxin) in cases of difficult to control arrhythmias or atrial fibrillation

Monitoring by auscultation, ECG and Holter monitor will help determine if the medication is controlling the abnormal heart rhythm

Interactions with other Drugs

Cisapride, acepromazine, quinidine, procainamide, tricyclic antidepressants (clomipramine, amitriptyline, doxepin) carry a small risk in veterinary patients of inducing a worsening arrhythmia
Calcium channel blockers (Verapamil, Diltiazem) may increase risk for low blood pressure and low heart rates
The doctors at CVCA have taken this into account, however, please feel free to contact CVCA regarding any concurrent medications your pet may be prescribed

Standard Dosage Forms

Sotalol HCL Tablets – 80mg, 120mg, 160mg, 240mg

Synonyms: (Sotalol, Betapace)