Studies and Publications from CVCA Doctors

Home » Studies and Publications from CVCA Doctors

At CVCA Cardiac Care for Pets, we strive to provide excellent medical care. This is not only through the daily care of our patients but also through input into the ever-growing base of knowledge of the veterinary cardiac patient. We are proud to contribute to veterinary literature through our collaboration within our team and our veterinary academic and industry partners.

Our very own Steven Rosenthal, DVM, DACVIM (Cardiology) has co-authored a chapter in a new reference book, Clinical Small Animal Internal Medicine, edited by David Bruyette! This is a handy text for veterinary professionals and covers a wide array of clinically-relevant material!

Cardiac/Cardiology Studies

2022, March - The longitudinal outcome of canine (K9) myxomatous mitral valve disease (LOOK-Mitral) registry: Baseline treatment characteristics

The longitudinal outcome of canine (K9) myxomatous mitral valve disease (LOOK-Mitral) registry: Baseline treatment characteristics

Published March 2022

Journal of veterinary cardiology

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Bill Tyrrell, DVM, Diplomate, ACVIM (Cardiology)

2021, October - Arrhythmogenic Right Ventricular Cardiomyopathy in the Bulldog: Evaluation of Clinical and Histopathologic Features, Progression, and Outcome in 71 Dogs (2004 – 2016)

Arrhythmogenic Right Ventricular Cardiomyopathy in the Bulldog: Evaluation of Clinical and Histopathologic Features, Progression, and Outcome in 71 Dogs (2004 – 2016)

Published October 2021

Journal of Veterinary Cardiology

CVCA Doctors Involved: Sarah L. Holdt, VMD, Diplomate, ACVIM (Cardiology), Neal Peckens, DVM, Diplomate, ACVIM (Cardiology), Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Rick Cober, DVM, MS, Diplomate, ACVIM (Cardiology)

2021, April - Acquired Stenosis of All Four Heart Valves in a Boxer Mix Dog

M Boothe, SL Rosenthal. CASE. 2021 Apr; 10.1016/j.case.2021.02.005

2020, March - Management of Heart Failure

David Bruyette, Steven L. Rosenthal, Mark Oyama, et al. Clinical Small Animal Internal Medicine. 2020 Mar; 1.3.19. 978-1-118-49703-6

2020, March - Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study

Adrian Boswood, Sonya G. Gordon, Steven L. Rosenthal, et al. Journal of Veterinary Internal Medicine. 2020 Mar; 34: 1108‐ 1118. 10.1111/jvim.15753

2020, March - Echocardiographic and electrocardiographic evaluation of North American Irish Wolfhounds.

William D. Tyrrell, Jr., Jonathan Abbott, Steven L. Rosenthal, Mariellen Dentino, Frances Abrams. Journal of Veterinary Internal Medicine. 2020 Mar; 34(2): 581–590. 10.1111/jvim.15709

2019, December - Pedigree analysis of atrial fibrillation in Irish Wolfhounds supports a high heritability with a dominant mode of inheritance.

Samantha L. Fousse, William D. Tyrrell, Mariellen E. Dentino, Frances L. Abrams, Steven L. Rosenthal, Joshua A. Stern. Canine Genetics and Epidemiology. 2019 Dec 9; 6:11. 10.1186/s40575-019-0079-y

2019, February - A QIL1 variant associated with ventricular arrhythmias and sudden cardiac death in the juvenile Rhodesian Ridgeback Dog.

A QIL1 Variant Associated with Ventricular Arrhythmias and Sudden Cardiac Death in the Juvenile Rhodesian Ridgeback Dog

Published February 2019

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Jess Weidman, DVM, Diplomate, ACVIM (Cardiology)

2018, December - Taurine deficiency and dilated cardiomyopathy in golden retrievers fed commercial diets; Joshua Stern, et al

Taurine deficiency and dilated cardiomyopathy in golden retrievers fed commercial diets; Joshua Stern, et al .

PLOS ONE open access

Published December 2018

CVCA Doctors Involved: Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology), Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology)

2018, November - ECG of the Month

ECG of the Month - November 2018

Published November 2018

JAVMA.

CVCA Doctors Involved: William Tyrrell, DVM, Diplomate, ACVIM (Cardiology), Rick Cober, DVM, MS, Diplomate, ACVIM (Cardiology)

2018, April - Quiz: Hypertrophic Cardiomyopathy in Cats

Quiz: Hypertrophic Cardiomyopathy in Cats

Published April 2018

Clinician's Brief

CVCA Doctors Involved: Matthew Boothe, DVM, Resident in Cardiology

2018, January - Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Preclinical Myxomatous Mitral Valve Disease Receiving Pimobendan or Placebo: The EPIC Study.

Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Preclinical Myxomatous Mitral Valve Disease Receiving Pimobendan or Placebo: The EPIC Study.

Published January 2018

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology)

2017, December - Successful balloon angioplasty of pulmonary artery stenosis in two cats and associated complications.

Successful balloon angioplasty of pulmonary artery stenosis in two cats and associated complications.

Published December 2017

Journal of veterinary cardiology

CVCA Doctors Involved: William Tyrrell, DVM, Diplomate, ACVIM (Cardiology), Kristin Jacob, DVM, Diplomate, ACVIM (Cardiology)

2017, November - Reference intervals and allometric scaling of two-dimensional echocardiographic measurements in 150 healthy cats.

Reference intervals and allometric scaling of two-dimensional echocardiographic measurements in 150 healthy cats.

Published November 2017

Journal of Veterinary Medical Science

CVCA Doctors Involved: Stephanie Savino, DVM, Resident in Cardiology

2017, June - ECG of the Month

ECG of the Month - June 2017

Published June 2017

JAVMA

CVCA Doctors Involved: Matthew Boothe, DVM, Resident in Cardiology

2017, March - Breed-Specific Vertebral Heart Scale for the Dachshund.

Breed-Specific Vertebral Heart Scale for the Dachshund.

Published March 2017

Journal of the American Animal Hospital Association

CVCA Doctors Involved: Sarah Clay Bell, DVM, Diplomate, ACVIM (Cardiology)

2016, December - Right ventricular involvement in feline hypertrophic cardiomyopathy.

Right ventricular involvement in feline hypertrophic cardiomyopathy.

Published December 2016

Journal of veterinary cardiology

CVCA Doctors Involved: Stephanie Savino, DVM, Resident in Cardiology

2016, November - Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial.

Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial.

Published November 2016

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology)

2016, July - Impact of collaborative care on survival time for dogs with congestive heart failure and revenue for attending primary care veterinarians

Impact of collaborative care on survival time for dogs with congestive heart failure and revenue for attending primary care veterinarians

Journal of the American Veterinary Medical Association

Published July 2016

CVCA Doctors Involved: Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology), Neal Peckens, DVM, Diplomate, ACVIM (Cardiology)

2016, June - Pentoxifylline as adjunct therapy to long-term clinical management of a right-to-left patent ductus arteriosus

Pentoxifylline as adjunct therapy to long-term clinical management of a right-
to-left patent ductus arteriosus

Published June 2016

The Canadian Veterinary Journal

CVCA Doctors Involved: Elizabeth Turner, DVM, Resident in Cardiology

2016, May - Ventricular arrhythmias in Rhodesian Ridgebacks with a family history of sudden death and results of a pedigree analysis for potential inheritance patterns.

Ventricular arrhythmias in Rhodesian Ridgebacks with a family history of sudden death and results of a pedigree analysis for potential inheritance patterns.

Published May 2016

JAVMA

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Jess Weidman, DVM, Diplomate, ACVIM (Cardiology)

2015, December - Secondary prevention of cardiogenic arterial thromboembolism in the cat: The double-blind, randomized, positive-controlled feline arterial thromboembolism; clopidogrel vs. aspirin trial (FAT CAT).

Secondary prevention of cardiogenic arterial thromboembolism in the cat: The double-blind, randomized, positive-controlled feline arterial thromboembolism; clopidogrel vs. aspirin trial (FAT CAT).

Published December 2015

Journal of veterinary cardiology

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Kristin Jacob, DVM, Diplomate, ACVIM (Cardiology)

2015, May - Elevated calcium transients and increased myofibrillar power generation cause cardiac hypercontractility in a model of Noonan Syndrome with Multiple Lentigines.

Elevated calcium transients and increased myofibrillar power generation cause cardiac hypercontractility in a model of Noonan Syndrome with Multiple Lentigines.

Published May 2015

American Journal of Physiology – Heart and Circulatory Physiology

CVCA Doctors Involved: Sarah Clay Bell, DVM, Diplomate, ACVIM (Cardiology)

2014, October - Relationship of Plasma N-terminal Pro-brain Natriuretic Peptide Concentrations to Heart Failure Classification and Cause of Respiratory Distress in Dogs Using a 2nd Generation ELISA Assay

Relationship of Plasma N-terminal Pro-brain Natriuretic Peptide Concentrations to Heart Failure Classification and Cause of Respiratory Distress in Dogs Using a 2nd Generation ELISA Assay

Published October 2014

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology)

2014, June - Cardiac involvement secondary to mediastinal lymphoma in a cat: regression with chemotherapy.

Cardiac involvement secondary to mediastinal lymphoma in a cat: regression with chemotherapy.

Published June 2014

Journal of veterinary cardiology

CVCA Doctors Involved: Julia Shih, VMD, Diplomate, ACVIM (Cardiology)

2014, June - Survey of Cardiac Pathologies in Captive Striped Skunks (Mehpitis mephitis)

Survey of Cardiac Pathologies in Captice Striped Skunks (Mehpitis mephitis)

Published June 2014

Journal of Zoo and Wildlife Medicine

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology)

2012, December - Pharmacokinetics of oral pimobendan in healthy cats.

Pharmacokinetics of oral pimobendan in healthy cats.

Published December 2012

Journal of veterinary cardiology

CVCA Doctors Involved: Emily Westphal, DVM, Diplomate, ACVIM (Cardiology)

2012, October - Emergency Presentations Associated with Cardiovascular Disease in Exotic Herbivores

Emergency Presentations Associated with Cardiovascular Disease in Exotic Herbivores

Published October 2012

Journal of Exotic Pet Medicine

CVCA Doctors Involved: Emily Westphal, DVM, Diplomate, ACVIM (Cardiology)

2012, February - Prediction of first onset of congestive heart failure in dogs with degenerative mitral valve disease: the PREDICT cohort study.

Prediction of first onset of congestive heart failure in dogs with degenerative mitral valve disease: the PREDICT cohort study.

Published February 2012

Journal of veterinary cardiology

CVCA Doctors Involved: Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology), Katie Meier, DVM, Diplomate, ACVIM (Cardiology)

2011, December - Pharmacodynamic effects of ivabradine, a negative chronotropic agent, in healthy cats.

Pharmacodynamic effects of ivabradine, a negative chronotropic agent, in healthy cats.

Published December 2011

Journal of veterinary cardiology

CVCA Doctors Involved: Rick Cober, DVM, MS, Diplomate, ACVIM (Cardiology)

2011, August - White-coat effect on systemic blood pressure in retired racing Greyhounds.

White-coat effect on systemic blood pressure in retired racing Greyhounds.

Published August 2011

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Rick Cober, DVM, MS, Diplomate, ACVIM (Cardiology)

2011, March - ECG of the Month

ECG of the Month - March 2011

Published March 2011

JAVMA

CVCA Doctors Involved: Rick Cober, DVM, MS, Diplomate, ACVIM (Cardiology)

2011, January - Multicenter evaluation of plasma N-terminal probrain natriuretic peptide (NT-pro BNP) as a biochemical screening test for asymptomatic (occult) cardiomyopathy in cats.

Multicenter evaluation of plasma N-terminal probrain natriuretic peptide (NT-pro BNP) as a biochemical screening test for asymptomatic (occult) cardiomyopathy in cats.

Published January 2011

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology)

2011 - Utility of Cardiac Troponin I in differentiating between underlying etiologies of pericardial effusion in the canine patient.

Utility of Cardiac Troponin I in differentiating between underlying etiologies of pericardial effusion in the canine patient.

Published 2011

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Bill Tyrrell, DVM, Diplomate, ACVIM (Cardiology), Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology)

2009, December - Assessment of serum N-terminal pro-B-type natriuretic peptide concentration for differentiation of congestive heart failure from primary respiratory tract disease as the case of respiratory signs in dogs

Assessment of serum N-terminal pro-B-type natriuretic peptide concentration for differentiation of congestive heart failure from primary respiratory tract disease as the case of respiratory signs in dogs

Published December 2009

JAVMA

CVCA Doctors Involved: Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology)

2009, June - Adverse effects of intravenous amiodarone in 5 dogs.

Adverse effects of intravenous amiodarone in 5 dogs.

Published June 2009

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Rick Cober, DVM, MS, Diplomate, ACVIM (Cardiology)

2009, April - Utility of plasma NT-Pro BNP to distinguish between CHF and non-cardiac causes of CHF in cats

Utility of plasma NT-Pro BNP to distinguish between CHF and non-cardiac causes of CHF in cats

Published April 2009

Journal of veterinary cardiology

CVCA Doctors Involved: Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology)

2009 - Myocardial Infarction

Myocardial Infarction

Published 2009

Small Animal Critical Care Medicine

CVCA Doctors Involved: Katie Meier, DVM, Diplomate, ACVIM (Cardiology)

2008, June - Calculation of pressure half-time.

Calculation of pressure half-time.

Published June 2008

Journal of veterinary cardiology

CVCA Doctors Involved: Jess Weidman, DVM, Diplomate, ACVIM (Cardiology)

2008, June - ECG of the month

ECG of the month

Published June 2008

JAVMA

CVCA Doctors Involved: Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology), Neal Peckens, DVM, Diplomate, ACVIM (Cardiology)

2008, June - Review of Rapid Interpretation of Heart and Lung Sounds (3rd edition)

Review of Rapid Interpretation of Heart and Lung Sounds (3rd edition)

Published June 2008

JAVMA

CVCA Doctors Involved: Sara Beth Bordelon, DVM, MS, Diplomate, ACVIM (Cardiology)

2008, June - Endovascular retrieval of embolized jugular catheter fragments in three dogs using a nitinol gooseneck snare.

Endovascular retrieval of embolized jugular catheter fragments in three dogs using a nitinol gooseneck snare.

Published June 2008

Journal of veterinary cardiology

CVCA Doctors Involved: Sara Beth Bordelon, DVM, MS, Diplomate, ACVIM (Cardiology)

2007, October - Results of the veterinary enalapril trial to prove reduction in onset of heart failure in dogs chronically treated with enalapril alone for compensated, naturally occurring mitral valve insufficiency

Results of the veterinary enalapril trial to prove reduction in onset of heart failure in dogs chronically treated with enalapril alone for compensated, naturally occurring mitral valve insufficiency

Published October 2007

JAVMA

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Jennifer Sidley, DVM, Diplomate, ACVIM (Cardiology)

2007 - Pericardial Effusion in Cats: A Retrospective Study of Clinical Findings and Outcome in 146 Cats

Pericardial Effusion in Cats: A Retrospective Study of Clinical Findings and Outcome in 146 Cats

Published 2007

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Katie Meier, DVM, Diplomate, ACVIM (Cardiology)

2006, November - ECG of the Month

ECG of the Month.

Published November 2006

JAVMA

CVCA Doctors Involved: Katie Meier, DVM, Diplomate, ACVIM (Cardiology)

2006, May - Association of pimobendan with ventricular arrhythmias in dogs with congestive heart failure.

Association of pimobendan with ventricular arrhythmias in dogs with congestive heart failure.

Published May 2006

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Bill Tyrrell, DVM, Diplomate, ACVIM (Cardiology), Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology)

2006 - Echocardiography in a horse with cor pulmonale and right heart failure due to recurrent airway obstruction.

Echocardiography in a horse with cor pulmonale and right heart failure due to recurrent airway obstruction.

Published 2006

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Kristin Jacob, DVM, Diplomate, ACVIM (Cardiology)

2005, March - Measurement of M-mode echocardiographic parameters in healthy adult Maine Coon cats

Measurement of M-mode echocardiographic parameters in healthy adult Maine Coon cats

Published March 2005

JAVMA

CVCA Doctors Involved: Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology), Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), William Tyrrell, DVM, Diplomate, ACVIM (Cardiology),

2004 - Corticosteroid-Associated Congestive Heart Failure in 12 Cats.

Corticosteroid-Associated Congestive Heart Failure in 12 Cats.

Published 2004

Internal Journal of Applied Research in Veterinary Medicine.

CVCA Doctors Involved: Kristin Jacob, DVM, Diplomate, ACVIM (Cardiology)

2003, September - Noninvasive transthoracic temporary pacing in dogs.

Noninvasive transthoracic temporary pacing in dogs.

Published September 2003

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Jennifer Sidley, DVM, Diplomate, ACVIM (Cardiology)

2003, August - Use of pericardial fluid pH to distinguish between idiopathic and neoplastic effusions.

Use of pericardial fluid pH to distinguish between idiopathic and neoplastic effusions.

Published August 2003

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Kristin Jacob, DVM, Diplomate, ACVIM (Cardiology)

2003, February - Arterial Thromboembolism in Cats: Acute Crisis in 127 Cases (1992-2001) and Long-Term Management with Low-Dose Aspirin in 24 Cases.

Arterial Thromboembolism in Cats: Acute Crisis in 127 Cases (1992-2001) and Long-Term Management with Low-Dose Aspirin in 24 Cases.

Published February 2003

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Kristin Jacob, DVM, Diplomate, ACVIM (Cardiology)

2002, October - Percutaneous balloon pericardiotomy as a treatment for recurrent pericardial effusion in 6 dogs.

Percutaneous balloon pericardiotomy as a treatment for recurrent pericardial effusion in 6 dogs.

Published October 2002

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Jennifer Sidley, DVM, Diplomate, ACVIM (Cardiology)

2002, September/October - Supravalvular mitral stenosis in a cat.

Supravalvular mitral stenosis in a cat.

Published September-October 2002

Journal of the American Animal Hospital Association.

CVCA Doctors Involved: Kristin Jacob, DVM, Diplomate, ACVIM (Cardiology)

2002, September - Effects of long term administration of enalapril on clinical indicators of renal function in dogs with compensated mitral regurgitation.

Effects of long term administration of enalapril on clinical indicators of renal function in dogs with compensated mitral regurgitation.

Published September 2002

JAVMA

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Jennifer Sidley, DVM, Diplomate, ACVIM (Cardiology)

2001, December - Natural history of hypertrophic cardiomyopathy and aortic thromboembolism in a family of domestic shorthair cats.

Natural history of hypertrophic cardiomyopathy and aortic thromboembolism in a family of domestic shorthair cats.

Published December 2001

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Jennifer Sidley, DVM, Diplomate, ACVIM (Cardiology)

2000, August - Heartworm infection in cats: 50 cases (1985-1997).

Heartworm infection in cats: 50 cases (1985-1997).

Published August 2000

JAVMA

CVCA Doctors Involved: Jennifer Sidley, DVM, Diplomate, ACVIM (Cardiology)

1998 - Left ventricular outflow velocities in 23 miniature bull terriers: variation from other breeds.

Left ventricular outflow velocities in 23 miniature bull terriers: variation from other breeds.

Published 1998

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology)

1996, November - Idiopathic dilated cardiomyopathy in Dalmatians. 9 cases( 1990-1995)

Idiopathic dilated cardiomyopathy in Dalmatians. 9 cases( 1990-1995)

Published November 1996

JAVMA

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology)

1995, November - Effects of electrocardiograph frequency filters on P-QRS-T amplitudes of the feline electrocardiogram.

Effects of electrocardiograph frequency filters on P-QRS-T amplitudes of the feline electrocardiogram.

Published November 1995

American journal of veterinary research

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology)

1995, March - Diastolic mitral regurgitation detected by pulsed wave Doppler echocardiography and color flow Doppler mapping in five dogs and two cats with second and third degree atrioventricular block.

Diastolic mitral regurgitation detected by pulsed wave Doppler echocardiography and color flow Doppler mapping in five dogs and two cats with second and third degree atrioventricular block.

Published March 1995

Veterinary Radiology and Ultrasound

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology)

Severe hypertrophic cardiomyopathy in 10 young ragdoll cats.

Journal of Veterinary Internal Medicine

CVCA Doctors Involved: Steven Rosenthal, DVM, Diplomate, ACVIM (Cardiology), Bill Tyrrell, DVM, Diplomate, ACVIM (Cardiology), Bonnie Lefbom, DVM, Diplomate, ACVIM (Cardiology)