Sildenafil Drug Handout

What is Sildenafil?

Sildenafil belongs to a group of medications that delay the breakdown of the enzyme phosphodiesterase 5. It increases substances in the body that induce vasodilation (relaxation of arteries/ veins) within certain regions of blood vessels, like those found in the lungs.


  • Pulmonary Hypertension secondary to primary respiratory disease (chronic bronchitis, COPD, pulmonary fibrosis), chronic mitral valve disease or thromboembolic disease (blood clots).

Adverse Effects

Please contact CVCA should any of these symptoms be noted

  • Low risk for decreased appetite, vomiting or diarrhea
  • Low blood pressure resulting in lethargy and weakness
  • Skin flushing

Client Information

  • Can be given with or without food
  • Comes in tablet form, but can be reformulated into capsules and liquid suspensions
  • Commonly used with other cardiac and respiratory medications
  • Does not require any specific monitoring

Interactions with Other Drugs

Standard Dosage Forms

Synonyms: Viagra, Revatio